THERAPEUTIC RNA FOR TREATING CANCER

This disclosure relates to the field of therapeutic RNA to treat cancer, in particular advanced solid tumors such as metastatic (Stage IV) or unresectable localized cancer. Disclosed herein are compositions, uses, and methods for treatment of cancers. Administration of therapeutic RNAs to a patient...

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Bibliographische Detailangaben
Hauptverfasser: KRANZ, Lena Mareen, MUIK, Alexander, VORMEHR, Mathias, FELLERMEIER-KOPF, Sina, SAHIN, Ugur, DIEKMANN, Jan, EISEL, David
Format: Patent
Sprache:eng
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Zusammenfassung:This disclosure relates to the field of therapeutic RNA to treat cancer, in particular advanced solid tumors such as metastatic (Stage IV) or unresectable localized cancer. Disclosed herein are compositions, uses, and methods for treatment of cancers. Administration of therapeutic RNAs to a patient having cancer disclosed herein can reduce tumor size, prolong time to progressive disease, and/or protect against metastasis and/or recurrence of the tumor and ultimately extend survival time.