Lumen insertable capsule

A capsule device (100) suitable for insertion into a lumen, such as a gastrointestinal lumen, of a subject. The capsule device (100) comprises: a capsule housing (110, 120), a drug chamber (B) configured to accommodate a drug substance, the drug chamber leading to a drug outlet (190), - an actuation...

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Hauptverfasser: JEPSEN, Jacob Pyung Hwa, LARSEN, André, MOURIDSEN, Brian, STICKER, Drago, GHAZAL, Aghiad
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creator JEPSEN, Jacob Pyung Hwa
LARSEN, André
MOURIDSEN, Brian
STICKER, Drago
GHAZAL, Aghiad
description A capsule device (100) suitable for insertion into a lumen, such as a gastrointestinal lumen, of a subject. The capsule device (100) comprises: a capsule housing (110, 120), a drug chamber (B) configured to accommodate a drug substance, the drug chamber leading to a drug outlet (190), - an actuation chamber (A), - a movable separator (160) arranged between the actuation chamber and the drug chamber, wherein movement of the movable separator expels drug substance from the drug chamber (B) through the drug outlet (190), and - a gas generator (140, 150) configured actuatable to generate pressurized gas in the actuation chamber (A) for exerting mechanical load on the moveable separator (160) to expel the drug substance. A burst gate (170) is arranged between the gas generator (140, 150) and the movable separator (160), the burst gate (170) configured to release mechanical load onto the movable separator (160) upon increase in gas pressure in the actuation chamber (A) above a threshold pressure level to thereby initiate expelling of the drug substance.
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subjects DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
title Lumen insertable capsule
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