A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF
The present invention belongs to the technical field of medicines, and relates to a class of fused ring compounds, and the preparation and use thereof. Test results show that the compounds can significantly inhibit the ATM kinase activity, have a good selectivity for the ATM target, and have the pha...
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creator | FAN, Lixue LI, Chunna ZHAO, Chuanwu ZHANG, Yan CHEN, Liqian QI, Fei WANG, Zhenyu JIANG, Chunhua CHAI, Xiaoling ZHANG, Chaozai |
description | The present invention belongs to the technical field of medicines, and relates to a class of fused ring compounds, and the preparation and use thereof. Test results show that the compounds can significantly inhibit the ATM kinase activity, have a good selectivity for the ATM target, and have the pharmaceutical use of treating cancer. |
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Test results show that the compounds can significantly inhibit the ATM kinase activity, have a good selectivity for the ATM target, and have the pharmaceutical use of treating cancer.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF |
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