SENOLYTIC COMPOUNDS AND COMPOSITIONS
There is described the use of an agent in the manufacture of a therapy for the treatment or alleviation of a senescence-associated disease, disorder or effect, wherein the agent is selected from one or more of A42548, A425619, alpha lipoic acid, apigenin, Artemisinin, BML-288, BTBHQ, EGCG, fluphenaz...
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| creator | ZGLINCKI, Thomas von MIWA, Satomi CONLON, Nichola Jane YOUNG, Malcolm Philip |
| description | There is described the use of an agent in the manufacture of a therapy for the treatment or alleviation of a senescence-associated disease, disorder or effect, wherein the agent is selected from one or more of A42548, A425619, alpha lipoic acid, apigenin, Artemisinin, BML-288, BTBHQ, EGCG, fluphenazine dihydrochloride, honokiol, LE300, magnolol, niclosamide, nicotinamide, nordihydroguaiaretic acid, quercetin, resveratrol and a mitochondrial uncoupler. There is also described the use of a mitochondrial uncoupler as an agent for the treatment of a senescence-associated disorder; and the use of an uncoupler in association with a senolytic agent. |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS |
| title | SENOLYTIC COMPOUNDS AND COMPOSITIONS |
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