Fusion protein including complement pathway inhibitor and angiogenesis inhibitor and use thereof

Provided is a fusion protein dimer comprising a protein which specifically binds to the extracellular domain of CRIg or a fragment thereof and VEGF. The protein may inhibit complement-related pathways and also may efficiently regulate angiogenesis. Thus, the fusion protein dimer can be effectively a...

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Hauptverfasser:	LEE, Byoung Chul, CHUNG, Eu Ddeum, KIM, Donggeon, CHANG, Jihoon, RYU, Soomin
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	LEE, Byoung Chul CHUNG, Eu Ddeum KIM, Donggeon CHANG, Jihoon RYU, Soomin
description	Provided is a fusion protein dimer comprising a protein which specifically binds to the extracellular domain of CRIg or a fragment thereof and VEGF. The protein may inhibit complement-related pathways and also may efficiently regulate angiogenesis. Thus, the fusion protein dimer can be effectively applied to the treatment and prevention of complement-related diseases, in particular, eye diseases such as macular degeneration, and thus, has high industrial applicability.
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subjects	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Fusion protein including complement pathway inhibitor and angiogenesis inhibitor and use thereof
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