Novel polypeptides with improved proteolytic stability, and methods of preparing and using same

The present invention includes methods of improving proteolytic stability of a polypeptide, comprising alkylating at least one selected from the group consisting of a N 5 terminus amino group, the NH group of the N-terminus first internal amide bond, another primary amino group, a thiol group and a...

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Hauptverfasser:	KUMAR, Krishna, RAMAN, Venkata, MONTANARI, Vittorio, BEINBORN, Martin
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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