Crystalline RET inhibitor

Provided herein is a crystalline form of selpercatinib useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders, and methods of making this crystalline form.

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Hauptverfasser: BHARDWAJ, Rajni Miglani, KJELL, Douglas Patton, VISWANATH, Shekhar Krishna, SELBO, Jon Gordon, KERR, Mark Steven, MERRITT, Jeremy Miles
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creator BHARDWAJ, Rajni Miglani
KJELL, Douglas Patton
VISWANATH, Shekhar Krishna
SELBO, Jon Gordon
KERR, Mark Steven
MERRITT, Jeremy Miles
description Provided herein is a crystalline form of selpercatinib useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders, and methods of making this crystalline form.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Crystalline RET inhibitor
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