Tablet formulation for CGRP-active compounds
Colloidal Silica (Cob-O-Sil) Cosieve Microcrystalne Celluloe(Acl) Milled dispersion Screen (optional) Mannili NaCl Powder Crocarmellse Sodum Blend/Lubdcate Coseved Cob-O-Sil/Avicel Sodium Stearyl Fumarate Compress to Tablet R"R The present invention is directed to compositions comprising an ext...
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| creator | IKEDA, Craig B XU, Wei ALLAIN, Leonardo Resende LUPTON, Lisa NOFSINGER, Rebecca EICKHOFF, W. Mark FLANAGAN Jr., Francis J XI, Hanmi MAROTA, Melanie PATEL, Paresh B JOHNSON, Mary Ann BROWN, Chad D |
| description | Colloidal Silica (Cob-O-Sil) Cosieve Microcrystalne Celluloe(Acl) Milled dispersion Screen (optional) Mannili NaCl Powder Crocarmellse Sodum Blend/Lubdcate Coseved Cob-O-Sil/Avicel Sodium Stearyl Fumarate Compress to Tablet R"R The present invention is directed to compositions comprising an extmdate or solid solution of a compound, or a salt thereof, of Formula I (API): Formula I, wherein "Ra" is independently H or -F, in a water-soluble polymer matrix which further comprises a disintegration system allowing a tablet made therefrom to rapidly disintegrate in the environment in which the API is to be released. |
| format | Patent |
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Mark ; FLANAGAN Jr., Francis J ; XI, Hanmi ; MAROTA, Melanie ; PATEL, Paresh B ; JOHNSON, Mary Ann ; BROWN, Chad D</creator><creatorcontrib>IKEDA, Craig B ; XU, Wei ; ALLAIN, Leonardo Resende ; LUPTON, Lisa ; NOFSINGER, Rebecca ; EICKHOFF, W. 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Mark</creatorcontrib><creatorcontrib>FLANAGAN Jr., Francis J</creatorcontrib><creatorcontrib>XI, Hanmi</creatorcontrib><creatorcontrib>MAROTA, Melanie</creatorcontrib><creatorcontrib>PATEL, Paresh B</creatorcontrib><creatorcontrib>JOHNSON, Mary Ann</creatorcontrib><creatorcontrib>BROWN, Chad D</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>IKEDA, Craig B</au><au>XU, Wei</au><au>ALLAIN, Leonardo Resende</au><au>LUPTON, Lisa</au><au>NOFSINGER, Rebecca</au><au>EICKHOFF, W. Mark</au><au>FLANAGAN Jr., Francis J</au><au>XI, Hanmi</au><au>MAROTA, Melanie</au><au>PATEL, Paresh B</au><au>JOHNSON, Mary Ann</au><au>BROWN, Chad D</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Tablet formulation for CGRP-active compounds</title><date>2021-11-04</date><risdate>2021</risdate><abstract>Colloidal Silica (Cob-O-Sil) Cosieve Microcrystalne Celluloe(Acl) Milled dispersion Screen (optional) Mannili NaCl Powder Crocarmellse Sodum Blend/Lubdcate Coseved Cob-O-Sil/Avicel Sodium Stearyl Fumarate Compress to Tablet R"R The present invention is directed to compositions comprising an extmdate or solid solution of a compound, or a salt thereof, of Formula I (API): Formula I, wherein "Ra" is independently H or -F, in a water-soluble polymer matrix which further comprises a disintegration system allowing a tablet made therefrom to rapidly disintegrate in the environment in which the API is to be released.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Tablet formulation for CGRP-active compounds |
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