L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF
The invention provides the L-valinate ester of a hydroxypropylthiazolidine carboxamide derivative of formula (I), (2S)-3-([1,1'-biphenyl]-4-ylsulfonyl)-N-[(1S)-3 hydroxy-1- phenylpropyl]-1,3-thiazolidine-2- carboxamide, as well as salts and crystal polymorphs thereof. The compound inhibits the...
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| creator | POMEL, Vincent SCHWARZ, Matthias JORAND-LEBRUN, Catherine QUATTROPANI, Anna NAXOS PAGE, Patrick |
| description | The invention provides the L-valinate ester of a hydroxypropylthiazolidine carboxamide derivative of formula (I), (2S)-3-([1,1'-biphenyl]-4-ylsulfonyl)-N-[(1S)-3 hydroxy-1- phenylpropyl]-1,3-thiazolidine-2- carboxamide, as well as salts and crystal polymorphs thereof. The compound inhibits the prostaglandin F receptor (PGF2alpha) and is useful in the treatment of disorders such as preterm labor at the early gestational stage or dysmennorrhea. |
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The compound inhibits the prostaglandin F receptor (PGF2alpha) and is useful in the treatment of disorders such as preterm labor at the early gestational stage or dysmennorrhea.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF |
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