ANTI-OX40L ANTIBODY, ANTI-OX40L/ANTI-TNFα BISPECIFIC ANTIBODY, AND USES THEREOF
The present invention relates to a novel antibody that specifically binds to OX40L and a bispecific antibody that specifically binds to OX40L and TNFα and, in particular, to: an antibody or a bispecific antibody that specifically binds to human OX40L to effectively inhibit the binding between OX40 a...
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| creator | PARK, Bum Chan PARK, Jae Eun HA, Gyong Sik LEE, Hyun Mi CHO, Kyu Eun JUNG, Seung Hee LEE, Yoon Jung CHOI, Jong Ryoul LEE, Chung Min KANG, Hyeon Ju KIM, Soo Young SHIM, Eun Young YOO, Jung Min |
| description | The present invention relates to a novel antibody that specifically binds to OX40L and a bispecific antibody that specifically binds to OX40L and TNFα and, in particular, to: an antibody or a bispecific antibody that specifically binds to human OX40L to effectively inhibit the binding between OX40 and an OX40 receptor; a nucleic acid encoding the antibody; an expression vector comprising the nucleic acid; a transformant comprising the expression vector; a method for producing the antibody; a pharmaceutical composition for the treatment of autoimmune diseases or inflammatory diseases, comprising the antibody; a composition for the diagnosis of autoimmune diseases or inflammatory diseases, comprising the antibody; a method for diagnosing autoimmune diseases or inflammatory diseases by using the antibody; and a method for providing information for the diagnosis of autoimmune diseases or inflammatory diseases by using the antibody; and a kit for providing same. |
| format | Patent |
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PARK, Jae Eun ; HA, Gyong Sik ; LEE, Hyun Mi ; CHO, Kyu Eun ; JUNG, Seung Hee ; LEE, Yoon Jung ; CHOI, Jong Ryoul ; LEE, Chung Min ; KANG, Hyeon Ju ; KIM, Soo Young ; SHIM, Eun Young ; YOO, Jung Min</creatorcontrib><description>The present invention relates to a novel antibody that specifically binds to OX40L and a bispecific antibody that specifically binds to OX40L and TNFα and, in particular, to: an antibody or a bispecific antibody that specifically binds to human OX40L to effectively inhibit the binding between OX40 and an OX40 receptor; a nucleic acid encoding the antibody; an expression vector comprising the nucleic acid; a transformant comprising the expression vector; a method for producing the antibody; a pharmaceutical composition for the treatment of autoimmune diseases or inflammatory diseases, comprising the antibody; a composition for the diagnosis of autoimmune diseases or inflammatory diseases, comprising the antibody; a method for diagnosing autoimmune diseases or inflammatory diseases by using the antibody; 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a nucleic acid encoding the antibody; an expression vector comprising the nucleic acid; a transformant comprising the expression vector; a method for producing the antibody; a pharmaceutical composition for the treatment of autoimmune diseases or inflammatory diseases, comprising the antibody; a composition for the diagnosis of autoimmune diseases or inflammatory diseases, comprising the antibody; a method for diagnosing autoimmune diseases or inflammatory diseases by using the antibody; and a method for providing information for the diagnosis of autoimmune diseases or inflammatory diseases by using the antibody; and a kit for providing same.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING |
| title | ANTI-OX40L ANTIBODY, ANTI-OX40L/ANTI-TNFα BISPECIFIC ANTIBODY, AND USES THEREOF |
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