Chimeric antigen receptor specifically binding to CD 300c antigen or receptor thereof

The present invention relates to a chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof, and immune cells expressing same, or the like. The chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof according to the present invention...

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Hauptverfasser: JEON, Jaewon, KIM, Haneul, LEE, Suin
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creator JEON, Jaewon
KIM, Haneul
LEE, Suin
description The present invention relates to a chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof, and immune cells expressing same, or the like. The chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof according to the present invention specifically recognizes cancer cells expressing a CD300c antigen or CD300c receptor and directly effectively inhibits the growth of cancer, metastasis, or the like, and moreover, activates T cells and the like in the body through the inhibition of CD300c, and thereby can reduce side effects and also increase a cancer therapeutic effect, and thus is expected to be effectively used as an immunotherapeutic agent for various cancers.
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The chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof according to the present invention specifically recognizes cancer cells expressing a CD300c antigen or CD300c receptor and directly effectively inhibits the growth of cancer, metastasis, or the like, and moreover, activates T cells and the like in the body through the inhibition of CD300c, and thereby can reduce side effects and also increase a cancer therapeutic effect, and thus is expected to be effectively used as an immunotherapeutic agent for various cancers.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220616&amp;DB=EPODOC&amp;CC=AU&amp;NR=2020394279A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20220616&amp;DB=EPODOC&amp;CC=AU&amp;NR=2020394279A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JEON, Jaewon</creatorcontrib><creatorcontrib>KIM, Haneul</creatorcontrib><creatorcontrib>LEE, Suin</creatorcontrib><title>Chimeric antigen receptor specifically binding to CD 300c antigen or receptor thereof</title><description>The present invention relates to a chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof, and immune cells expressing same, or the like. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Chimeric antigen receptor specifically binding to CD 300c antigen or receptor thereof
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