Chimeric antigen receptor specifically binding to CD 300c antigen or receptor thereof

The present invention relates to a chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof, and immune cells expressing same, or the like. The chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof according to the present invention...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	JEON, Jaewon, KIM, Haneul, LEE, Suin
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof, and immune cells expressing same, or the like. The chimeric antigen receptor specifically binding to a CD300c antigen or a receptor thereof according to the present invention specifically recognizes cancer cells expressing a CD300c antigen or CD300c receptor and directly effectively inhibits the growth of cancer, metastasis, or the like, and moreover, activates T cells and the like in the body through the inhibition of CD300c, and thereby can reduce side effects and also increase a cancer therapeutic effect, and thus is expected to be effectively used as an immunotherapeutic agent for various cancers.