Methods of treatment with myosin modulator

Disclosed herein are methods of treatment comprising administering a therapeutically effective amount of a myosin modulator or a pharmaceutically acceptable salt thereof to a subject in need thereof and diagnostic methods useful in connection with those treatments. Due to observations unfolding in c...

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Hauptverfasser: ZHANG, David, DEL RIO, Carlos L, CARLSON, Timothy, LAMPL, Kathy L, MCDOWELL, Robert, KANE, Brian Edmund, FANG, Liang, HENZE, Marcus Patrick, LAMBING, Joseph, LI, Wanying, SEMIGRAN, Marc J, AUBELE, Danielle L, DESAI, Milind Y, FERNANDES, Sarah, NISSEN, Steve, MEALIFFE, Matthew Edwards, EDELBERG, Jay M, SEHL, Louis Charles, MA, Grace Yanfei, SEHNERT, Amy
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creator ZHANG, David
DEL RIO, Carlos L
CARLSON, Timothy
LAMPL, Kathy L
MCDOWELL, Robert
KANE, Brian Edmund
FANG, Liang
HENZE, Marcus Patrick
LAMBING, Joseph
LI, Wanying
SEMIGRAN, Marc J
AUBELE, Danielle L
DESAI, Milind Y
FERNANDES, Sarah
NISSEN, Steve
MEALIFFE, Matthew Edwards
EDELBERG, Jay M
SEHL, Louis Charles
MA, Grace Yanfei
SEHNERT, Amy
description Disclosed herein are methods of treatment comprising administering a therapeutically effective amount of a myosin modulator or a pharmaceutically acceptable salt thereof to a subject in need thereof and diagnostic methods useful in connection with those treatments. Due to observations unfolding in clinical trials with mavacamten and with mavacamten and other myosin inhibitors in the pre-clinical setting, new insights into how myosin inhibitors can be used beneficially to impact the disease state of HCM and other diseases are provided herein.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Methods of treatment with myosin modulator
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