Combination of ibuprofen and tramadol for relieving pain

The present invention relates to the combination of ibuprofen in the form of a pharmaceutically acceptable salt, and tramadol, or a pharmaceutical acceptable salt thereof, for use in the treatment of pain in humans, wherein the dosage of ibuprofen in the combination is comprised between 350 mg and 4...

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Hauptverfasser: DUART GONZALEZ, Ester, GÓMEZ CALVO, Antonia, SÁNCHEZ GARCÍA, Jose Angel, HORCAJADA CÓRDOBA, Raquel, SANZ MENÉNDEZ, Nuria, VARGAS CASTRILLÓN, Emilio, VICARIO DE LA TORRE, Marta, CALANDRIA PÉREZ, Carlos, MUÑOZ RUIZ, Ángel José, PORTOLÉS PÉREZ, Antonio, SANTÉ SERNA, Luis Narciso, GARCÍA ALONSO, Fernando, SALAS BUTRÓN, María del Rosario
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creator DUART GONZALEZ, Ester
GÓMEZ CALVO, Antonia
SÁNCHEZ GARCÍA, Jose Angel
HORCAJADA CÓRDOBA, Raquel
SANZ MENÉNDEZ, Nuria
VARGAS CASTRILLÓN, Emilio
VICARIO DE LA TORRE, Marta
CALANDRIA PÉREZ, Carlos
MUÑOZ RUIZ, Ángel José
PORTOLÉS PÉREZ, Antonio
SANTÉ SERNA, Luis Narciso
GARCÍA ALONSO, Fernando
SALAS BUTRÓN, María del Rosario
description The present invention relates to the combination of ibuprofen in the form of a pharmaceutically acceptable salt, and tramadol, or a pharmaceutical acceptable salt thereof, for use in the treatment of pain in humans, wherein the dosage of ibuprofen in the combination is comprised between 350 mg and 450 mg and the dosage of tramadol is comprised between 35 mg and 40 mg, expressed as equivalent weight of tramadol hydrochloride. The combination is suitable for the treatment of moderate to severe pain, of chronic or acute origin, and is particularly effective for those patients suffering from more intense pain. It also relates to a pharmaceutical composition comprising said fixed-dose combination of ibuprofen and tramadol.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Combination of ibuprofen and tramadol for relieving pain
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