Methods and compositions for comprehensive and high sensitivity detection of pathogens and drug resistance markers

Provided herein are methods of amplifying and detecting pathogens and drug resistance markers (e.g., antibiotic resistance genes) in complex samples (e.g., blood), as well as related panels and compositions (e.g., primers, probes, magnetic particles, systems, cartridges, and kits). The methods, pane...

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Hauptverfasser: MARTURANO, Joseph, SHIVERS, Robert Patrick, GAMERO, Daniel, BURGESS, Kelly N, SMITH, Roger, NAUFER, Mohamed Nabuan, LOWERY Jr., Thomas J, ESTRADA, Sandy, SNYDER, Jessica Lee, MANNING, Brendan John
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creator MARTURANO, Joseph
SHIVERS, Robert Patrick
GAMERO, Daniel
BURGESS, Kelly N
SMITH, Roger
NAUFER, Mohamed Nabuan
LOWERY Jr., Thomas J
ESTRADA, Sandy
SNYDER, Jessica Lee
MANNING, Brendan John
description Provided herein are methods of amplifying and detecting pathogens and drug resistance markers (e.g., antibiotic resistance genes) in complex samples (e.g., blood), as well as related panels and compositions (e.g., primers, probes, magnetic particles, systems, cartridges, and kits). The methods, panels, and compositions can be used for comprehensive detection of pathogens and drug resistance markers for patient identification, patient selection, optimization of therapies, and antimicrobial stewardship.
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subjects APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title Methods and compositions for comprehensive and high sensitivity detection of pathogens and drug resistance markers
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