Bispecific binding molecules that target the tumor microenvironment and an immune checkpoint protein

Bispecific binding proteins that bind ΙΡ-1β or IL-1R and a checkpoint protein are provided, together with methods of making the proteins. The checkpoint protein may be PD-1 or PD-L1. The binding proteins may have immunoglobulin-like structures that contain human Fab or scFv domains. A novel bispecif...

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Bibliographische Detailangaben

Hauptverfasser:	WANG, Jin, RAINEY, Godfrey Jonah
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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