Methods, compositions, and devices for solid-state synthesis of expandable polymers for use in single molecule sequencing

Methods, compositions, and devices for solid-state synthesis of expandable polymers for use in single molecule sequencing

Methods, compositions and devices for single molecule sequencing are provided, particularly for solid-state synthesis and processing of expandable polymers (e.g., Xpandomers), as well as methods and compositions for producing new expandable polymer constructs that provide more accurate sequence info...

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Bibliographische Detailangaben
Hauptverfasser: BERRIOS, Christian, LEHMANN, Taylor, AGUIRRE, Gerson, LEE, Michael, JACOBS, Aaron, TABONE, John, KELLER BARRETT, Salka, MCRUER, Robert N, VELLUCCI, Samantha, CORNING, Matthew, PRINDLE, Marc, CHANDRASEKAR, Jagadeeswaran, MERRILL, Lacey, THIESSEN, Greg, KOKORIS, Mark Stamatios
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
COMBINATORIAL CHEMISTRY
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
METALLURGY
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Zusammenfassung:Methods, compositions and devices for single molecule sequencing are provided, particularly for solid-state synthesis and processing of expandable polymers (e.g., Xpandomers), as well as methods and compositions for producing new expandable polymer constructs that provide more accurate sequence information when passed through a nanopore sensor.