Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives

Disclosed herein are non-natural amino acids and dolastatin analogs that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The dolastatin analogs can include a wide range of possible functionalities, but typically have at least one oxi...

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Hauptverfasser:	Atkinson, Kyle C, Biroc, Sandra, Marsden, Robin, Valenta, Ianina, Sun, Ying, Cook, Melissa, Kraynov, Vadim, Skidmore, Lillian, Pinkstaff, Jason, Szydlik, Angieszka, Miao, Zhenwal, Buss, Timothy
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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