BISPECIFIC BINDING PROTEINS AND USES THEREOF
The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The dis...
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| creator | Oberst, Michael Rainey, Godfrey Gao, Changshou Carlesso, Gianluca Kasturirangan, Srinath Herbst, Ronald Dobson, Claire Louise Seaman, Jonathan Morrow, Michelle Pollizzi, Kristen Drabic, Stacey Hammond, Scott A Manikwar, Prakash Mazor, Yariv Lobo, Brian Schofield, Darren Dovedi, Simon |
| description | The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject. |
| format | Patent |
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The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200723&DB=EPODOC&CC=AU&NR=2020204497A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200723&DB=EPODOC&CC=AU&NR=2020204497A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Oberst, Michael</creatorcontrib><creatorcontrib>Rainey, Godfrey</creatorcontrib><creatorcontrib>Gao, Changshou</creatorcontrib><creatorcontrib>Carlesso, Gianluca</creatorcontrib><creatorcontrib>Kasturirangan, Srinath</creatorcontrib><creatorcontrib>Herbst, Ronald</creatorcontrib><creatorcontrib>Dobson, Claire Louise</creatorcontrib><creatorcontrib>Seaman, Jonathan</creatorcontrib><creatorcontrib>Morrow, Michelle</creatorcontrib><creatorcontrib>Pollizzi, Kristen</creatorcontrib><creatorcontrib>Drabic, Stacey</creatorcontrib><creatorcontrib>Hammond, Scott A</creatorcontrib><creatorcontrib>Manikwar, Prakash</creatorcontrib><creatorcontrib>Mazor, Yariv</creatorcontrib><creatorcontrib>Lobo, Brian</creatorcontrib><creatorcontrib>Schofield, Darren</creatorcontrib><creatorcontrib>Dovedi, Simon</creatorcontrib><title>BISPECIFIC BINDING PROTEINS AND USES THEREOF</title><description>The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. 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The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | BISPECIFIC BINDING PROTEINS AND USES THEREOF |
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