Methods and compositions for generation of binding agents against cell surface antigens

Provided are methods and compositions for identifying binding polypeptides (e.g., antibodies or antigen binding fragments thereof) that specifically binds to a cell-surface antigen. The methods of the invention generally comprise contacting a variegated nucleic acid-display library of binding polype...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Yan, Shamah, Steve
Format: Patent
Sprache:eng
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