Pseudofab-based multispecific binding proteins
Binding proteins comprising a pseudoFab domain including a stabilised knockout domain and a second VH/VL that form a first functional antigen binding domain are provided. Multispecific binding proteins comprising at least one pseudoFab are also provided. Multispecific binding proteins, nucleic acids...
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| creator | LEUSCHNER, Wulf-Dirk ENGEL, Karl-Christian LANGE, Christian BEIL, Christian LEMOINE, Cendrine RAO, Ercole WEIL, Sandra LANGER, Thomas HOELPER, Soraya HESSLER, Gerhard SPINDLER, Nadja OEZGUER BRUEDERLE, Sevim |
| description | Binding proteins comprising a pseudoFab domain including a stabilised knockout domain and a second VH/VL that form a first functional antigen binding domain are provided. Multispecific binding proteins comprising at least one pseudoFab are also provided. Multispecific binding proteins, nucleic acids encoding binding proteins and multispecific binding proteins, expression vectors, host cells, pharmaceutical composition and methods of treatment administering the binding proteins or multispecific binding proteins described herein are also provided. |
| format | Patent |
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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | Pseudofab-based multispecific binding proteins |
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