Pyrimidone derivatives as selective cytotoxic agents against HIV infected cells

The present disclosure is directed to pyrimidone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or del...

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Bibliographische Detailangaben

Hauptverfasser:	CONVERSO, Antonella, NANTERMET, Philippe, FORSTER, Ashley, WANG, Deping, MITCHELL, Helen J, SHIPE, William Daniel, WANG, Cheng, EL MARROUNI, Abdellatif, FRIE, Jessica L, HUNTER, David N, SHA, Deyou, KUDUK, Scott D
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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