Pladienolide compounds and their use

The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome...

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Hauptverfasser:	REYNOLDS, Dominic, GERARD, Baudouin, KIRA, Kazunobu, TIVITMAHAISOON, Parcharee, GEARHART, Nicholas C, KOTAKE, Yoshihiko, NAGAO, Satoshi, KANADA SONOBE, Regina Mikie, COOK, Andrew, NEVALAINEN, Marta, LUO, Touping, HAO, Ming-Hong, ENDO, Atsushi, MARCAURELLE, Lisa A, O'SHEA, Morgan Welzel, ZHENG, Guo Zhu, MURAI, Norio, PALACINO, James, ARAI, Kenzo, ELLERY, Shelby, WANG, John, MIYANO, Masayuki, PRAJAPATI, Sudeep, KEANEY, Gregg F, LOWE, Jason T, LIU, Xiang
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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