Anti-TIGIT antibodies and uses thereof
Disclosed are a novel antibody specifically binding to the tumor-immunosuppressant, TIGIT (T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif [ITIM] domain) or an antigen-binding fragment thereof, a nucleic acid encoding the antibody or the antigen-binding fragment thereof, a v...
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| creator | LEE, Eun-Jung CHOI, Byung Hyun KO, Bong-Kook KIM, Kyu-Tae LEE, Jong-Seo JEONG, Eunjeong CHOI, Sunghyun LEE, Kwang-Hoon PARK, Ju Young PARK, Young Bong LEE, June Hyung SONG, Moo Young LEE, Na Rae CHANG, Nakho KIM, Ki Hong |
| description | Disclosed are a novel antibody specifically binding to the tumor-immunosuppressant, TIGIT (T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif [ITIM] domain) or an antigen-binding fragment thereof, a nucleic acid encoding the antibody or the antigen-binding fragment thereof, a vector and a host cell including the nucleic acid, a method for producing the antibody or the antigen-binding fragment thereof, a pharmaceutical composition containing the antibody or the antigen-binding fragment thereof as an active ingredient, and uses of the pharmaceutical composition. The antibody specifically binding to TIGIT or the antigen-binding fragment thereof and the pharmaceutical composition containing the same as an active ingredient are preferably used for the treatment of cancer or tumors. |
| format | Patent |
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The antibody specifically binding to TIGIT or the antigen-binding fragment thereof and the pharmaceutical composition containing the same as an active ingredient are preferably used for the treatment of cancer or tumors.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230622&DB=EPODOC&CC=AU&NR=2019229076B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230622&DB=EPODOC&CC=AU&NR=2019229076B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE, Eun-Jung</creatorcontrib><creatorcontrib>CHOI, Byung Hyun</creatorcontrib><creatorcontrib>KO, Bong-Kook</creatorcontrib><creatorcontrib>KIM, Kyu-Tae</creatorcontrib><creatorcontrib>LEE, Jong-Seo</creatorcontrib><creatorcontrib>JEONG, Eunjeong</creatorcontrib><creatorcontrib>CHOI, Sunghyun</creatorcontrib><creatorcontrib>LEE, Kwang-Hoon</creatorcontrib><creatorcontrib>PARK, Ju Young</creatorcontrib><creatorcontrib>PARK, Young Bong</creatorcontrib><creatorcontrib>LEE, June Hyung</creatorcontrib><creatorcontrib>SONG, Moo Young</creatorcontrib><creatorcontrib>LEE, Na Rae</creatorcontrib><creatorcontrib>CHANG, Nakho</creatorcontrib><creatorcontrib>KIM, Ki Hong</creatorcontrib><title>Anti-TIGIT antibodies and uses thereof</title><description>Disclosed are a novel antibody specifically binding to the tumor-immunosuppressant, TIGIT (T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif [ITIM] domain) or an antigen-binding fragment thereof, a nucleic acid encoding the antibody or the antigen-binding fragment thereof, a vector and a host cell including the nucleic acid, a method for producing the antibody or the antigen-binding fragment thereof, a pharmaceutical composition containing the antibody or the antigen-binding fragment thereof as an active ingredient, and uses of the pharmaceutical composition. The antibody specifically binding to TIGIT or the antigen-binding fragment thereof and the pharmaceutical composition containing the same as an active ingredient are preferably used for the treatment of cancer or tumors.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBzzCvJ1A3xdPcMUUgEMpPyUzJTi4HMFIXSYiCjJCO1KDU_jYeBNS0xpziVF0pzM6i4uYY4e-imFuTHpxYXJCan5qWWxDuGGhkYWhoZWRqYmzk5GRkTqQwA_zsoLw</recordid><startdate>20230622</startdate><enddate>20230622</enddate><creator>LEE, Eun-Jung</creator><creator>CHOI, Byung Hyun</creator><creator>KO, Bong-Kook</creator><creator>KIM, Kyu-Tae</creator><creator>LEE, Jong-Seo</creator><creator>JEONG, Eunjeong</creator><creator>CHOI, Sunghyun</creator><creator>LEE, Kwang-Hoon</creator><creator>PARK, Ju Young</creator><creator>PARK, Young Bong</creator><creator>LEE, June Hyung</creator><creator>SONG, Moo Young</creator><creator>LEE, Na Rae</creator><creator>CHANG, Nakho</creator><creator>KIM, Ki Hong</creator><scope>EVB</scope></search><sort><creationdate>20230622</creationdate><title>Anti-TIGIT antibodies and uses thereof</title><author>LEE, Eun-Jung ; CHOI, Byung Hyun ; KO, Bong-Kook ; KIM, Kyu-Tae ; LEE, Jong-Seo ; JEONG, Eunjeong ; CHOI, Sunghyun ; LEE, Kwang-Hoon ; PARK, Ju Young ; PARK, Young Bong ; LEE, June Hyung ; SONG, Moo Young ; LEE, Na Rae ; CHANG, Nakho ; KIM, Ki Hong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2019229076BB23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LEE, Eun-Jung</creatorcontrib><creatorcontrib>CHOI, Byung Hyun</creatorcontrib><creatorcontrib>KO, Bong-Kook</creatorcontrib><creatorcontrib>KIM, Kyu-Tae</creatorcontrib><creatorcontrib>LEE, Jong-Seo</creatorcontrib><creatorcontrib>JEONG, Eunjeong</creatorcontrib><creatorcontrib>CHOI, Sunghyun</creatorcontrib><creatorcontrib>LEE, Kwang-Hoon</creatorcontrib><creatorcontrib>PARK, Ju Young</creatorcontrib><creatorcontrib>PARK, Young Bong</creatorcontrib><creatorcontrib>LEE, June Hyung</creatorcontrib><creatorcontrib>SONG, Moo Young</creatorcontrib><creatorcontrib>LEE, Na Rae</creatorcontrib><creatorcontrib>CHANG, Nakho</creatorcontrib><creatorcontrib>KIM, Ki Hong</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEE, Eun-Jung</au><au>CHOI, Byung Hyun</au><au>KO, Bong-Kook</au><au>KIM, Kyu-Tae</au><au>LEE, Jong-Seo</au><au>JEONG, Eunjeong</au><au>CHOI, Sunghyun</au><au>LEE, Kwang-Hoon</au><au>PARK, Ju Young</au><au>PARK, Young Bong</au><au>LEE, June Hyung</au><au>SONG, Moo Young</au><au>LEE, Na Rae</au><au>CHANG, Nakho</au><au>KIM, Ki Hong</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Anti-TIGIT antibodies and uses thereof</title><date>2023-06-22</date><risdate>2023</risdate><abstract>Disclosed are a novel antibody specifically binding to the tumor-immunosuppressant, TIGIT (T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif [ITIM] domain) or an antigen-binding fragment thereof, a nucleic acid encoding the antibody or the antigen-binding fragment thereof, a vector and a host cell including the nucleic acid, a method for producing the antibody or the antigen-binding fragment thereof, a pharmaceutical composition containing the antibody or the antigen-binding fragment thereof as an active ingredient, and uses of the pharmaceutical composition. 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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Anti-TIGIT antibodies and uses thereof |
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