P2X7 modulators

The present invention is directed to compounds of Formulas (I, la, lla and Ilb). The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, la, Ila and Ilb). Methods of making and using the compounds of Formulas (I, la, Ila and Ilb) are also within the scope of th...

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Hauptverfasser: Alcazar Vaca, Manuel Jesus, Allison, Brett D, Wall, Jessica L, Deng, Xiaohu, Andres Gil, Jose Ignacio, Mani, Neelakandha S, Chrovian, Christa C, Swanson, Devin M, Coate, Heather R, Rech, Jason C, Dvorak, Curt A, Stenne, Brice M, Letavic, Michael A, De Angelis, Meri, Liang, Jimmy T, Soyode-Johnson, Akinola, Gelin, Christine F, Savall, Brad M
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creator Alcazar Vaca, Manuel Jesus
Allison, Brett D
Wall, Jessica L
Deng, Xiaohu
Andres Gil, Jose Ignacio
Mani, Neelakandha S
Chrovian, Christa C
Swanson, Devin M
Coate, Heather R
Rech, Jason C
Dvorak, Curt A
Stenne, Brice M
Letavic, Michael A
De Angelis, Meri
Liang, Jimmy T
Soyode-Johnson, Akinola
Gelin, Christine F
Savall, Brad M
description The present invention is directed to compounds of Formulas (I, la, lla and Ilb). The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, la, Ila and Ilb). Methods of making and using the compounds of Formulas (I, la, Ila and Ilb) are also within the scope of the invention.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title P2X7 modulators
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