Technologies for oligonucleotide preparation

Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.

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Bibliographische Detailangaben
Hauptverfasser: BOMMINENI, Gopal Reddy, ALAM, Mohammed Rowshon, SHIMIZU, Mamoru, STANDLEY, Stephany Michelle, KORBOUKH, Ilia, BUTLER, David Charles Donnell, ADUDA, Vincent, VARGEESE, Chandra, KANDASAMY, Pachamuthu, BOWMAN, Keith Andrew, TRIPATHI, Snehlata
Format: Patent
Sprache:eng
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Zusammenfassung:Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.