Acid addition salts of an orally available gonadotropin-releasing hormone receptor antagonist

The invention relates to non-deliquescent acid addition salts of elagolix with strong acids, for example selected from the group consisting of sulfuric acid and hydrochloric acid, to processes for their preparation and to a pharmaceutical composition comprising one of said salts, preferably in an ef...

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Hauptverfasser: Schreiner, Erwin Paul, Martin, Nolwenn, Silberberger, Herbert
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creator Schreiner, Erwin Paul
Martin, Nolwenn
Silberberger, Herbert
description The invention relates to non-deliquescent acid addition salts of elagolix with strong acids, for example selected from the group consisting of sulfuric acid and hydrochloric acid, to processes for their preparation and to a pharmaceutical composition comprising one of said salts, preferably in an effective and/or predetermined amount, wherein the pharmaceutical composition can be used as a medicament, in particular for the treatment of endometriosis and uterine fibroids.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Acid addition salts of an orally available gonadotropin-releasing hormone receptor antagonist
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