sGC stimulators
The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (N...
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| creator | Jung, Joon Iyengar, Rajesh R Nakai, Takashi Mermerian, Ara Lee, Thomas Wai-Ho Jia, James Rennie, Glen Robert Barden, Timothy Claude Germano, Peter Tang, Kim Iyer, Karthik Im, G-Yoon Jamie Renhowe, Paul Allan |
| description | The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP) might be desirable. Various compounds are disclosed, including those of Formula (I). |
| format | Patent |
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Various compounds are disclosed, including those of Formula (I).</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220630&DB=EPODOC&CC=AU&NR=2017356887B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220630&DB=EPODOC&CC=AU&NR=2017356887B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Jung, Joon</creatorcontrib><creatorcontrib>Iyengar, Rajesh R</creatorcontrib><creatorcontrib>Nakai, Takashi</creatorcontrib><creatorcontrib>Mermerian, Ara</creatorcontrib><creatorcontrib>Lee, Thomas Wai-Ho</creatorcontrib><creatorcontrib>Jia, James</creatorcontrib><creatorcontrib>Rennie, Glen Robert</creatorcontrib><creatorcontrib>Barden, Timothy Claude</creatorcontrib><creatorcontrib>Germano, Peter</creatorcontrib><creatorcontrib>Tang, Kim</creatorcontrib><creatorcontrib>Iyer, Karthik</creatorcontrib><creatorcontrib>Im, G-Yoon Jamie</creatorcontrib><creatorcontrib>Renhowe, Paul Allan</creatorcontrib><title>sGC stimulators</title><description>The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP) might be desirable. 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Various compounds are disclosed, including those of Formula (I).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | sGC stimulators |
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