Compounds and compositions as inhibitors of endosomal toll-like receptors

The invention disclosed herein relates to 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridinyl compounds and 4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridinyl compounds of Formula (A), pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of autoimmune diseases.

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Hauptverfasser: Jiang, Tao, Knoepfel, Thomas, Zhang, Yi, Deane, Jonathan, Zhang, Guobao, Mutnick, Daniel, Jiang, Songchun, Syka, Peter, Alper, Phillip, Michellys, Pierre-Yves, Pei, Wei
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creator Jiang, Tao
Knoepfel, Thomas
Zhang, Yi
Deane, Jonathan
Zhang, Guobao
Mutnick, Daniel
Jiang, Songchun
Syka, Peter
Alper, Phillip
Michellys, Pierre-Yves
Pei, Wei
description The invention disclosed herein relates to 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridinyl compounds and 4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridinyl compounds of Formula (A), pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of autoimmune diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Compounds and compositions as inhibitors of endosomal toll-like receptors
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