Compositions and methods for delivering messenger RNA

The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions...

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Hauptverfasser: Palmer, Lorne Ralph, Reid, Stephen P, Yaworski, Edward D, Judge, Adam, Lam, Kieu Mong, Heyes, James, Abrams, Michael J
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creator Palmer, Lorne Ralph
Reid, Stephen P
Yaworski, Edward D
Judge, Adam
Lam, Kieu Mong
Heyes, James
Abrams, Michael J
description The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title Compositions and methods for delivering messenger RNA
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