Compositions and methods for delivering messenger RNA
The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions...
Gespeichert in:
Hauptverfasser: | , , , , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | Palmer, Lorne Ralph Reid, Stephen P Yaworski, Edward D Judge, Adam Lam, Kieu Mong Heyes, James Abrams, Michael J |
description | The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2017286980A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2017286980A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2017286980A13</originalsourceid><addsrcrecordid>eNrjZDB1zs8tyC_OLMnMzytWSMxLUchNLcnITylWSMsvUkhJzcksSy3KzEsHChcXp-alpxYpBPk58jCwpiXmFKfyQmluBmU31xBnD93Ugvz41OKCxOTUvNSSeMdQIwNDcyMLM0sLA0dDY-JUAQAk8y4K</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Compositions and methods for delivering messenger RNA</title><source>esp@cenet</source><creator>Palmer, Lorne Ralph ; Reid, Stephen P ; Yaworski, Edward D ; Judge, Adam ; Lam, Kieu Mong ; Heyes, James ; Abrams, Michael J</creator><creatorcontrib>Palmer, Lorne Ralph ; Reid, Stephen P ; Yaworski, Edward D ; Judge, Adam ; Lam, Kieu Mong ; Heyes, James ; Abrams, Michael J</creatorcontrib><description>The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190117&DB=EPODOC&CC=AU&NR=2017286980A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190117&DB=EPODOC&CC=AU&NR=2017286980A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Palmer, Lorne Ralph</creatorcontrib><creatorcontrib>Reid, Stephen P</creatorcontrib><creatorcontrib>Yaworski, Edward D</creatorcontrib><creatorcontrib>Judge, Adam</creatorcontrib><creatorcontrib>Lam, Kieu Mong</creatorcontrib><creatorcontrib>Heyes, James</creatorcontrib><creatorcontrib>Abrams, Michael J</creatorcontrib><title>Compositions and methods for delivering messenger RNA</title><description>The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB1zs8tyC_OLMnMzytWSMxLUchNLcnITylWSMsvUkhJzcksSy3KzEsHChcXp-alpxYpBPk58jCwpiXmFKfyQmluBmU31xBnD93Ugvz41OKCxOTUvNSSeMdQIwNDcyMLM0sLA0dDY-JUAQAk8y4K</recordid><startdate>20190117</startdate><enddate>20190117</enddate><creator>Palmer, Lorne Ralph</creator><creator>Reid, Stephen P</creator><creator>Yaworski, Edward D</creator><creator>Judge, Adam</creator><creator>Lam, Kieu Mong</creator><creator>Heyes, James</creator><creator>Abrams, Michael J</creator><scope>EVB</scope></search><sort><creationdate>20190117</creationdate><title>Compositions and methods for delivering messenger RNA</title><author>Palmer, Lorne Ralph ; Reid, Stephen P ; Yaworski, Edward D ; Judge, Adam ; Lam, Kieu Mong ; Heyes, James ; Abrams, Michael J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2017286980A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2019</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Palmer, Lorne Ralph</creatorcontrib><creatorcontrib>Reid, Stephen P</creatorcontrib><creatorcontrib>Yaworski, Edward D</creatorcontrib><creatorcontrib>Judge, Adam</creatorcontrib><creatorcontrib>Lam, Kieu Mong</creatorcontrib><creatorcontrib>Heyes, James</creatorcontrib><creatorcontrib>Abrams, Michael J</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Palmer, Lorne Ralph</au><au>Reid, Stephen P</au><au>Yaworski, Edward D</au><au>Judge, Adam</au><au>Lam, Kieu Mong</au><au>Heyes, James</au><au>Abrams, Michael J</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Compositions and methods for delivering messenger RNA</title><date>2019-01-17</date><risdate>2019</risdate><abstract>The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_AU2017286980A1 |
source | esp@cenet |
subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
title | Compositions and methods for delivering messenger RNA |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T19%3A15%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Palmer,%20Lorne%20Ralph&rft.date=2019-01-17&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2017286980A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |