THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS
The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SÁNCHEZ-QUESADA, Jorge MEDINA PADILLA, Miguel DE CRISTOBAL BLANCO, Javier PALOMO NICOLAU, Francisco PÉREZ DE LA CRUZ MORENO, María Ángeles MARTÍNEZ MONTERO, Olga HERRERO SANTOS, Susana RODRÍGUEZ SALGUERO, Beatriz DOMÍNGUEZ CORREA, Juan Manuel FUERTES HUERTA, Ana LÓPEZ OGALLA, Javier |
| description | The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2017248556BB2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2017248556BB2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2017248556BB23</originalsourceid><addsrcrecordid>eNrjZNAM8fB0dPF0jPL38XTx9HN18fT3cw1WcAxWcA_21jVW8PTz8HTyDPEPCuZhYE1LzClO5YXS3Awqbq4hzh66qQX58anFBYnJqXmpJfGOoUYGhuZGJhampmZOTkbGRCoDAAfuJcI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS</title><source>esp@cenet</source><creator>SÁNCHEZ-QUESADA, Jorge ; MEDINA PADILLA, Miguel ; DE CRISTOBAL BLANCO, Javier ; PALOMO NICOLAU, Francisco ; PÉREZ DE LA CRUZ MORENO, María Ángeles ; MARTÍNEZ MONTERO, Olga ; HERRERO SANTOS, Susana ; RODRÍGUEZ SALGUERO, Beatriz ; DOMÍNGUEZ CORREA, Juan Manuel ; FUERTES HUERTA, Ana ; LÓPEZ OGALLA, Javier</creator><creatorcontrib>SÁNCHEZ-QUESADA, Jorge ; MEDINA PADILLA, Miguel ; DE CRISTOBAL BLANCO, Javier ; PALOMO NICOLAU, Francisco ; PÉREZ DE LA CRUZ MORENO, María Ángeles ; MARTÍNEZ MONTERO, Olga ; HERRERO SANTOS, Susana ; RODRÍGUEZ SALGUERO, Beatriz ; DOMÍNGUEZ CORREA, Juan Manuel ; FUERTES HUERTA, Ana ; LÓPEZ OGALLA, Javier</creatorcontrib><description>The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180809&DB=EPODOC&CC=AU&NR=2017248556B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180809&DB=EPODOC&CC=AU&NR=2017248556B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SÁNCHEZ-QUESADA, Jorge</creatorcontrib><creatorcontrib>MEDINA PADILLA, Miguel</creatorcontrib><creatorcontrib>DE CRISTOBAL BLANCO, Javier</creatorcontrib><creatorcontrib>PALOMO NICOLAU, Francisco</creatorcontrib><creatorcontrib>PÉREZ DE LA CRUZ MORENO, María Ángeles</creatorcontrib><creatorcontrib>MARTÍNEZ MONTERO, Olga</creatorcontrib><creatorcontrib>HERRERO SANTOS, Susana</creatorcontrib><creatorcontrib>RODRÍGUEZ SALGUERO, Beatriz</creatorcontrib><creatorcontrib>DOMÍNGUEZ CORREA, Juan Manuel</creatorcontrib><creatorcontrib>FUERTES HUERTA, Ana</creatorcontrib><creatorcontrib>LÓPEZ OGALLA, Javier</creatorcontrib><title>THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS</title><description>The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAM8fB0dPF0jPL38XTx9HN18fT3cw1WcAxWcA_21jVW8PTz8HTyDPEPCuZhYE1LzClO5YXS3Awqbq4hzh66qQX58anFBYnJqXmpJfGOoUYGhuZGJhampmZOTkbGRCoDAAfuJcI</recordid><startdate>20180809</startdate><enddate>20180809</enddate><creator>SÁNCHEZ-QUESADA, Jorge</creator><creator>MEDINA PADILLA, Miguel</creator><creator>DE CRISTOBAL BLANCO, Javier</creator><creator>PALOMO NICOLAU, Francisco</creator><creator>PÉREZ DE LA CRUZ MORENO, María Ángeles</creator><creator>MARTÍNEZ MONTERO, Olga</creator><creator>HERRERO SANTOS, Susana</creator><creator>RODRÍGUEZ SALGUERO, Beatriz</creator><creator>DOMÍNGUEZ CORREA, Juan Manuel</creator><creator>FUERTES HUERTA, Ana</creator><creator>LÓPEZ OGALLA, Javier</creator><scope>EVB</scope></search><sort><creationdate>20180809</creationdate><title>THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS</title><author>SÁNCHEZ-QUESADA, Jorge ; MEDINA PADILLA, Miguel ; DE CRISTOBAL BLANCO, Javier ; PALOMO NICOLAU, Francisco ; PÉREZ DE LA CRUZ MORENO, María Ángeles ; MARTÍNEZ MONTERO, Olga ; HERRERO SANTOS, Susana ; RODRÍGUEZ SALGUERO, Beatriz ; DOMÍNGUEZ CORREA, Juan Manuel ; FUERTES HUERTA, Ana ; LÓPEZ OGALLA, Javier</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2017248556BB23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SÁNCHEZ-QUESADA, Jorge</creatorcontrib><creatorcontrib>MEDINA PADILLA, Miguel</creatorcontrib><creatorcontrib>DE CRISTOBAL BLANCO, Javier</creatorcontrib><creatorcontrib>PALOMO NICOLAU, Francisco</creatorcontrib><creatorcontrib>PÉREZ DE LA CRUZ MORENO, María Ángeles</creatorcontrib><creatorcontrib>MARTÍNEZ MONTERO, Olga</creatorcontrib><creatorcontrib>HERRERO SANTOS, Susana</creatorcontrib><creatorcontrib>RODRÍGUEZ SALGUERO, Beatriz</creatorcontrib><creatorcontrib>DOMÍNGUEZ CORREA, Juan Manuel</creatorcontrib><creatorcontrib>FUERTES HUERTA, Ana</creatorcontrib><creatorcontrib>LÓPEZ OGALLA, Javier</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SÁNCHEZ-QUESADA, Jorge</au><au>MEDINA PADILLA, Miguel</au><au>DE CRISTOBAL BLANCO, Javier</au><au>PALOMO NICOLAU, Francisco</au><au>PÉREZ DE LA CRUZ MORENO, María Ángeles</au><au>MARTÍNEZ MONTERO, Olga</au><au>HERRERO SANTOS, Susana</au><au>RODRÍGUEZ SALGUERO, Beatriz</au><au>DOMÍNGUEZ CORREA, Juan Manuel</au><au>FUERTES HUERTA, Ana</au><au>LÓPEZ OGALLA, Javier</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS</title><date>2018-08-09</date><risdate>2018</risdate><abstract>The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_AU2017248556BB2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T01%3A56%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=S%C3%81NCHEZ-QUESADA,%20Jorge&rft.date=2018-08-09&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2017248556BB2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |