Polyimidazoles for use as bile acid sequestrants

H:\grs\Interwoven\NRPortbl\DCC\GRS\32291501 .docx-24/02/2017 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANT The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical com...

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Bibliographische Detailangaben
Hauptverfasser:	Connor, Eric, Zhang, Hongmin, Shao, Jun, Lee, Angela, Madsen, Deidre, Hecker, Scott, Zhang, Xinnan, Biyani, Kalpesh, Lees, Inez, Goka, Elizabeth, Cope, Michael James
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Zusammenfassung:	H:\grs\Interwoven\NRPortbl\DCC\GRS\32291501 .docx-24/02/2017 POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANT The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritus, irritable bowel syndrome diarrhea (IBS-D), bile acid malabsorption, and the like.