PIPERIDINE DERIVATIVES AS NK1 ANTAGONISTS
OF THE INVENTION A compound having the general structure shown in Formula 1: R' R2 Ar2 5 Ar' O R3 (I) or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example 10 various physiological disorders, sympto...
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| creator | HUANG, Xianhai PALIWAL, Sunil PALANI, Anandan RAO, Ashwin U XIAO, Dong SHAH, Sapna S SHIH, Neng-Yang WANG, Cheng WROBLESKI, Michelle Laci TSUI, Hon-Chung |
| description | OF THE INVENTION A compound having the general structure shown in Formula 1: R' R2 Ar2 5 Ar' O R3 (I) or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example 10 various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PIPERIDINE DERIVATIVES AS NK1 ANTAGONISTS |
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