Quinoline compounds, preparation method thereof, and use thereof as urate transporter inhibitor drug

The present invention discloses quinoline compounds, a preparation method thereof, and a use thereof as a urate transporter inhibitor drug. The compounds and salts, hydrates or solvates thereof provided in the present invention, as a selective uric acid reabsorption inhibitor, have the effect of red...

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Hauptverfasser: Chen, Yuanwei, Luo, Tongchuan, Fan, Lei, Zhang, Shaohua, Du, Wu, Li, Xinghai, Xu, Kexin, Chen, Ke
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creator Chen, Yuanwei
Luo, Tongchuan
Fan, Lei
Zhang, Shaohua
Du, Wu
Li, Xinghai
Xu, Kexin
Chen, Ke
description The present invention discloses quinoline compounds, a preparation method thereof, and a use thereof as a urate transporter inhibitor drug. The compounds and salts, hydrates or solvates thereof provided in the present invention, as a selective uric acid reabsorption inhibitor, have the effect of reducing uric acid in animal and human body and can treat hyperuricemia and gout by promoting secretion of uric acid from the body and reducing serum uric acid.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Quinoline compounds, preparation method thereof, and use thereof as urate transporter inhibitor drug
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