2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives as blockers of TASK-1 and TASK-2 channels, for the treatment of sleep-related breathing disorders
The invention relates to 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives as selective blockers of TASK-1 and TASK-3 channels, for the treatment and/or prevention of breathing disorders including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring...
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| creator | Mosig, Johanna Gehring, Doris Meier, Heinrich Rosenstein, Björn Albus, Udo Lustig, Klemens Müller, Thomas Delbeck, Martina Hahn, Michael Toschi, Luisella |
| description | The invention relates to 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives as selective blockers of TASK-1 and TASK-3 channels, for the treatment and/or prevention of breathing disorders including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives as blockers of TASK-1 and TASK-2 channels, for the treatment of sleep-related breathing disorders |
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