Modified chimeric receptors and related compositions and methods

Provided are chimeric receptors for engineering cells for adoptive therapy, including T cells, and the genetically engineered cells. In some embodiments, the chimeric receptors, such as chimeric antigen receptors (CARs) are modified in a junction region by one or more amino acid modifications such t...

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Bibliographische Detailangaben

Hauptverfasser:	Brahmandam, Archana, Thompson, Lucas James, Dubose, Robert F
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
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