Microfluidic model of the blood brain barrier
The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with o...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Lucchesi, Carol Sances, Samuel Hamilton, Geraldine Vatine, Gad Sareen, Dhruv Fraser, Jacob Levner, Daniel Kerns, S. Jordan Wen, Norman Hinojosa, Chris Svendsen, Clive |
| description | The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2016341880BB2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2016341880BB2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2016341880BB23</originalsourceid><addsrcrecordid>eNrjZND1zUwuyk_LKc1MyUxWyM1PSc1RyE9TKMlIVUjKyc9PUUgqSszMU0hKLCrKTC3iYWBNS8wpTuWF0twMKm6uIc4euqkF-fGpxQWJyal5qSXxjqFGBoZmxiaGFhYGTk5GxkQqAwCg-ys0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Microfluidic model of the blood brain barrier</title><source>esp@cenet</source><creator>Lucchesi, Carol ; Sances, Samuel ; Hamilton, Geraldine ; Vatine, Gad ; Sareen, Dhruv ; Fraser, Jacob ; Levner, Daniel ; Kerns, S. Jordan ; Wen, Norman ; Hinojosa, Chris ; Svendsen, Clive</creator><creatorcontrib>Lucchesi, Carol ; Sances, Samuel ; Hamilton, Geraldine ; Vatine, Gad ; Sareen, Dhruv ; Fraser, Jacob ; Levner, Daniel ; Kerns, S. Jordan ; Wen, Norman ; Hinojosa, Chris ; Svendsen, Clive</creatorcontrib><description>The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.</description><language>eng</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210121&DB=EPODOC&CC=AU&NR=2016341880B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210121&DB=EPODOC&CC=AU&NR=2016341880B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Lucchesi, Carol</creatorcontrib><creatorcontrib>Sances, Samuel</creatorcontrib><creatorcontrib>Hamilton, Geraldine</creatorcontrib><creatorcontrib>Vatine, Gad</creatorcontrib><creatorcontrib>Sareen, Dhruv</creatorcontrib><creatorcontrib>Fraser, Jacob</creatorcontrib><creatorcontrib>Levner, Daniel</creatorcontrib><creatorcontrib>Kerns, S. Jordan</creatorcontrib><creatorcontrib>Wen, Norman</creatorcontrib><creatorcontrib>Hinojosa, Chris</creatorcontrib><creatorcontrib>Svendsen, Clive</creatorcontrib><title>Microfluidic model of the blood brain barrier</title><description>The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.</description><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND1zUwuyk_LKc1MyUxWyM1PSc1RyE9TKMlIVUjKyc9PUUgqSszMU0hKLCrKTC3iYWBNS8wpTuWF0twMKm6uIc4euqkF-fGpxQWJyal5qSXxjqFGBoZmxiaGFhYGTk5GxkQqAwCg-ys0</recordid><startdate>20210121</startdate><enddate>20210121</enddate><creator>Lucchesi, Carol</creator><creator>Sances, Samuel</creator><creator>Hamilton, Geraldine</creator><creator>Vatine, Gad</creator><creator>Sareen, Dhruv</creator><creator>Fraser, Jacob</creator><creator>Levner, Daniel</creator><creator>Kerns, S. Jordan</creator><creator>Wen, Norman</creator><creator>Hinojosa, Chris</creator><creator>Svendsen, Clive</creator><scope>EVB</scope></search><sort><creationdate>20210121</creationdate><title>Microfluidic model of the blood brain barrier</title><author>Lucchesi, Carol ; Sances, Samuel ; Hamilton, Geraldine ; Vatine, Gad ; Sareen, Dhruv ; Fraser, Jacob ; Levner, Daniel ; Kerns, S. Jordan ; Wen, Norman ; Hinojosa, Chris ; Svendsen, Clive</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2016341880BB23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2021</creationdate><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Lucchesi, Carol</creatorcontrib><creatorcontrib>Sances, Samuel</creatorcontrib><creatorcontrib>Hamilton, Geraldine</creatorcontrib><creatorcontrib>Vatine, Gad</creatorcontrib><creatorcontrib>Sareen, Dhruv</creatorcontrib><creatorcontrib>Fraser, Jacob</creatorcontrib><creatorcontrib>Levner, Daniel</creatorcontrib><creatorcontrib>Kerns, S. Jordan</creatorcontrib><creatorcontrib>Wen, Norman</creatorcontrib><creatorcontrib>Hinojosa, Chris</creatorcontrib><creatorcontrib>Svendsen, Clive</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Lucchesi, Carol</au><au>Sances, Samuel</au><au>Hamilton, Geraldine</au><au>Vatine, Gad</au><au>Sareen, Dhruv</au><au>Fraser, Jacob</au><au>Levner, Daniel</au><au>Kerns, S. Jordan</au><au>Wen, Norman</au><au>Hinojosa, Chris</au><au>Svendsen, Clive</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Microfluidic model of the blood brain barrier</title><date>2021-01-21</date><risdate>2021</risdate><abstract>The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_AU2016341880BB2 |
| source | esp@cenet |
| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Microfluidic model of the blood brain barrier |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T08%3A28%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Lucchesi,%20Carol&rft.date=2021-01-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2016341880BB2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |