Triazole agonists of the APJ receptor
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structur...
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| creator | Cheng, Alan C Houze, Jonathan McGee, Lawrence R Olson, Steven H Chen, Xiaoqi Heath, Julie Anne Khakoo, Aarif Yusuf Yang, Kevin Fu, Zice Kaller, Matthew R Deignan, Jeffrey Ma, Zhihua Wang, Xiaodong Medina, Julio C Dransfield, Paul John Swaminath, Gayathri Horne, Daniel B Kopecky, David John Kayser, Frank Farrell, Robert P Chen, Ning Hedley, Simon J Connors, Richard V Yeh, Wen-Chen Debenedetto, Mikkel V Mihalic, Jeffrey T Nishimura, Nobuko Judd, Ted C Pattaropong, Vatee Chen, Yinhong Du, Xiaohui Lai, Su-Jen |
| description | Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures where the definitions of the variables are provided herein. |
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Compounds of Formula I and Formula II have the following structures where the definitions of the variables are provided herein.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Triazole agonists of the APJ receptor |
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