Triazole agonists of the APJ receptor

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structur...

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Bibliographische Detailangaben
Hauptverfasser:	Cheng, Alan C, Houze, Jonathan, McGee, Lawrence R, Olson, Steven H, Chen, Xiaoqi, Heath, Julie Anne, Khakoo, Aarif Yusuf, Yang, Kevin, Fu, Zice, Kaller, Matthew R, Deignan, Jeffrey, Ma, Zhihua, Wang, Xiaodong, Medina, Julio C, Dransfield, Paul John, Swaminath, Gayathri, Horne, Daniel B, Kopecky, David John, Kayser, Frank, Farrell, Robert P, Chen, Ning, Hedley, Simon J, Connors, Richard V, Yeh, Wen-Chen, Debenedetto, Mikkel V, Mihalic, Jeffrey T, Nishimura, Nobuko, Judd, Ted C, Pattaropong, Vatee, Chen, Yinhong, Du, Xiaohui, Lai, Su-Jen
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures where the definitions of the variables are provided herein.