Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same
The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotr...
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| creator | Jang, Young Koo Kim, Ji Yeon Cha, Soo Bong Cho, Nahm Ryune Min, Hye Kyung Jung, Hyo Jun Choi, Eun Ju Lee, Ji Won Han, Seung Nam Chung, Jin Yong Ham, Seung Mo Maeng, Cheol Young Lee, Ju Young Shin, Yong Je Kim, Yong Gil Joung, Chan Mi Park, Jong Sil Ryu, Eun Ju Park, Chun Eung |
| description | The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5. |
| format | Patent |
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The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200116&DB=EPODOC&CC=AU&NR=2016224227B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200116&DB=EPODOC&CC=AU&NR=2016224227B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Jang, Young Koo</creatorcontrib><creatorcontrib>Kim, Ji Yeon</creatorcontrib><creatorcontrib>Cha, Soo Bong</creatorcontrib><creatorcontrib>Cho, Nahm Ryune</creatorcontrib><creatorcontrib>Min, Hye Kyung</creatorcontrib><creatorcontrib>Jung, Hyo Jun</creatorcontrib><creatorcontrib>Choi, Eun Ju</creatorcontrib><creatorcontrib>Lee, Ji Won</creatorcontrib><creatorcontrib>Han, Seung Nam</creatorcontrib><creatorcontrib>Chung, Jin Yong</creatorcontrib><creatorcontrib>Ham, Seung Mo</creatorcontrib><creatorcontrib>Maeng, Cheol Young</creatorcontrib><creatorcontrib>Lee, Ju Young</creatorcontrib><creatorcontrib>Shin, Yong Je</creatorcontrib><creatorcontrib>Kim, Yong Gil</creatorcontrib><creatorcontrib>Joung, Chan Mi</creatorcontrib><creatorcontrib>Park, Jong Sil</creatorcontrib><creatorcontrib>Ryu, Eun Ju</creatorcontrib><creatorcontrib>Park, Chun Eung</creatorcontrib><title>Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same</title><description>The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. 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The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same |
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