Ligand-cytotoxicity drug conjugate, preparing method therefor, and application thereof

Provided are a ligand-cytotoxicity drug conjugate with a general formula of PC-L-Dr, a preparing method therefor, and applications of the ligand-cytotoxicity drug conjugate and pharmaceutical compositions comprising the same in preparing drugs for treating cancers by means of receptor regulation.

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Hauptverfasser: Qu, Bolei, Zhang, Lianshan, Zhang, Ying, Liang, Jindong, Li, Ang, Yu, Xiuzhao, Jiang, Guiyang, Zhang, Fuyao, Xu, Jianyan, Wang, Yali
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creator Qu, Bolei
Zhang, Lianshan
Zhang, Ying
Liang, Jindong
Li, Ang
Yu, Xiuzhao
Jiang, Guiyang
Zhang, Fuyao
Xu, Jianyan
Wang, Yali
description Provided are a ligand-cytotoxicity drug conjugate with a general formula of PC-L-Dr, a preparing method therefor, and applications of the ligand-cytotoxicity drug conjugate and pharmaceutical compositions comprising the same in preparing drugs for treating cancers by means of receptor regulation.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Ligand-cytotoxicity drug conjugate, preparing method therefor, and application thereof
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