Sulfonyl amide derivatives for the treatment of abnormal cell growth
Abstract The present invention relates to a compound of the formula I R4 -N HN-(CR2 R3), B 5 (R)m wherein R' to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also rel...
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| creator | Luzzio, Michael Joseph Xiao, Jun Hayward, Matthew Merrill Hulford, Catherine Angela Autry, Christopher Lowell Nelson, Kendra Louise Zhao, Xumiao Bhattacharya, Samit Kumar Freeman-Cook, Kevin Daniel |
| description | Abstract The present invention relates to a compound of the formula I R4 -N HN-(CR2 R3), B 5 (R)m wherein R' to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the 0 treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds. |
| format | Patent |
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Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the 0 treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180308&DB=EPODOC&CC=AU&NR=2016201820B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180308&DB=EPODOC&CC=AU&NR=2016201820B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Luzzio, Michael Joseph</creatorcontrib><creatorcontrib>Xiao, Jun</creatorcontrib><creatorcontrib>Hayward, Matthew Merrill</creatorcontrib><creatorcontrib>Hulford, Catherine Angela</creatorcontrib><creatorcontrib>Autry, Christopher Lowell</creatorcontrib><creatorcontrib>Nelson, Kendra Louise</creatorcontrib><creatorcontrib>Zhao, Xumiao</creatorcontrib><creatorcontrib>Bhattacharya, Samit Kumar</creatorcontrib><creatorcontrib>Freeman-Cook, Kevin Daniel</creatorcontrib><title>Sulfonyl amide derivatives for the treatment of abnormal cell growth</title><description>Abstract The present invention relates to a compound of the formula I R4 -N HN-(CR2 R3), B 5 (R)m wherein R' to R6, A, B, n and m are as defined herein. 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Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the 0 treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Sulfonyl amide derivatives for the treatment of abnormal cell growth |
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