Novel carboxylic acid compounds useful for inhibiting microsomal prostaglandin E2 synthase-1

The present invention provides compounds of Formula 1, or a pharmaceutically acceptable salts, thereof, where R, X, A, E, and G are as described herein, methods of preparing the compounds, and use of the compounds to treat pain and/or inflammation.

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Bibliographische Detailangaben
Hauptverfasser: Partridge, Katherine Marie, York, Jeremy Schulenburg, Kuklish, Steven Lee, Fisher, Matthew Joseph
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides compounds of Formula 1, or a pharmaceutically acceptable salts, thereof, where R, X, A, E, and G are as described herein, methods of preparing the compounds, and use of the compounds to treat pain and/or inflammation.