6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors

The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds, to p...

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Hauptverfasser: Alonso-De Diego, Sergio-Alvar, Delgado-Gonzalez, Oscar, Van Gool, Michiel Luc Maria, Martin-Martin, Maria Luz, Tresadern, Gary John, Conde-Ceide, Susana, Trabanco-Suarez, Andres Avelino, Andres-Gil, Jose Ignacio
Format: Patent
Sprache:eng
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