Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs

A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro- reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a bio...

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Hauptverfasser: Shulze, John Edwin, Ahlering, Michael Thomas, Yamamoto, Ronald Kenichi, Elicker, Robert John, Nguyen, Tien Thuy, Zoethout, Jelle Jurjen
Format: Patent
Sprache:eng
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Zusammenfassung:A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro- reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a biodegradable or bioerodable polymer. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided.