Methods for determining drug efficacy for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancers

Provided herein, in some embodiments, are methods of using certain cereblon- associated proteins, such as Aiolos, Ikaros, interferon (IFN), and IFN pathway proteins, casein kinase 1, alpha 1 (CSNK1A1), and ZFP9, as biomarkers for use in predicting and monitoring clinical sensitivity and therapeutic...

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Hauptverfasser: GANDHI, ANITA, KLIPPEL, ANKE, HAGNER, PATRICK, BREIDER, MIKE, HOLLENBACH, PAUL, TROTTER, MATTHEW WILLIAM BURNELL, COUTO, SUZANA STURLINI, HAVENS, COURTNEY G, CHOPRA, RAJESH, MACBETH, KYLE, WANG, MARIA YINGLIN, REN, YAN
Format: Patent
Sprache:eng
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