Composition of a non-nucleoside reverse transcriptase inhibitor
The invention encompasses a composition comprising the reverse transcriptase ("RT") inhibitor 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile sufficiently mixed in a concentration enhancing polymer...
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| creator | PLOEGER, KRISTIN J. M TATAVARTI, ADITYA S LOWINGER, MICHAEL BLOOM, COREY J BROOKHART, KATHERINE ANNE MARSAC, PATRICK JULES |
| description | The invention encompasses a composition comprising the reverse transcriptase ("RT") inhibitor 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile sufficiently mixed in a concentration enhancing polymer, and processes for making the same. The composition and processes of the present invention significantly improve the bioavailability of the aforementioned RT inhibitor, while maintaining physical stability. |
| format | Patent |
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M</au><au>TATAVARTI, ADITYA S</au><au>LOWINGER, MICHAEL</au><au>BLOOM, COREY J</au><au>BROOKHART, KATHERINE ANNE</au><au>MARSAC, PATRICK JULES</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Composition of a non-nucleoside reverse transcriptase inhibitor</title><date>2016-05-05</date><risdate>2016</risdate><abstract>The invention encompasses a composition comprising the reverse transcriptase ("RT") inhibitor 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile sufficiently mixed in a concentration enhancing polymer, and processes for making the same. The composition and processes of the present invention significantly improve the bioavailability of the aforementioned RT inhibitor, while maintaining physical stability.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING |
| title | Composition of a non-nucleoside reverse transcriptase inhibitor |
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