Lentiviral vectors containing an MHC class I, MHC class II, or beta-2 microglobulin upstream promoter sequence

The present invention relates to the insertion of an MHC class I, MHC Class II, or β2 microglobulin upstream promoter sequence into a lentiviral vector to increase viral titers. The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal use...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sarry, Emeline, Bauche, Cecile
Format: Patent
Sprache:eng
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