6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors

The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives of Formula (I) as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such...

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Bibliographische Detailangaben
Hauptverfasser:	Cid-Nunez, Jose Maria, Macdonald, Gregor James, Alonso-De Diego, Sergio-Alvar, Delgado-Gonzalez, Oscar, Van Gool, Michiel Luc Maria, Decorte, Annelies Marie Antonius, Megens, Antonius Adrianus Hendrikus Petrus, Trabanco-Suarez, Andres Avelino, Garcia-Molina, Aranzazu, Andres-Gil, Jose Ignacio
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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