FUSION PROTEINS FOR THE TREATMENT OF CNS

This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activity o...

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Bibliographische Detailangaben
Hauptverfasser: Gruskin, Elliott A, Iaci, Jennifer, Roy, Gargi, Zimber, Michael P, Caggiano, Anthony O
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activity of neuronal growth inhibitory molecules, as well as fusion proteins which includes a proteoglycan degrading domain and a domain capable of blocking and or over coming the activity of neuronal growth inhibitory molecules.